PUBLICATIONS 1994-1999
1999
- M. Giovarelli, P. Musiani, G. Garotta, R. Ebner, E. Di Carlo,
Y. Kim, P. Cappello, L. Rigamonti, P. Bernabei, F. Novelli, A.
Modesti, A. Coletti, A.K. Ferrie, P.-L. Lollini, S. Ruben, T.
Salcedo & G. Forni. A "stealth effect": adenocarcinoma cells
engineered to express TRAIL elude tumor-specific and allogeneic T
cell reactions. J. Immunol., 163: 4886-93, 1999. [Medline]
- E. Di Carlo, M.G. Diodoro, K. Boggio, A. Modesti, M. Modesti,
P. Nanni, G. Forni & P. Musiani. Analysis of mammary
carcinoma onset and progression in HER-2/neu oncogene transgenic
mice reveals a lobular origin. Lab. Invest., 79: 1261-9, 1999.
[Medline]
- R. De Vecchi, S.M. Pupa, S. Menard & P.-L. Lollini.
Correspondence re: Y. Chen et al., DNA vaccines encoding
full-length or truncated neu induce protective immunity against
neu-expressing mammary tumors. Cancer Res., 59: 4471-4472, 1999.
[Medline]
- P.-L. Lollini & V. Bronte. The immunotherapy of cancer:
understanding mechanisms through animal models. Minerva
Biotecnol., 11: 283-294, 1999.
- P.-L. Lollini & G. Forni. Specific and nonspecific
immunity in the prevention of spontaneous tumours. Immunol.
Today, 20: 347-350, 1999. [Medline]
- C. Rozera, D. Carlei, P.-L. Lollini, C. De Giovanni, P.
Musiani, E. Di Carlo, F. Belardelli & M. Ferrantini.
Interferon (IFN)-beta gene transfer into TS/A adenocarcinoma
cells and comparison with IFN-alpha: differential effects on
tumorigenicity and host response. Am. J. Pathol., 154: 1211-1222,
1999. [Medline]
- G. Bevilacqua, R. Giavazzi & P.-L. Lollini. Invasione e
metastasi. Pacini Editore, Pisa, 1999.
- P.-L. Lollini, C. De Giovanni & P. Nanni. Terapia genica
in oncologia. In: G. Bevilacqua, R. Giavazzi & P.-L. Lollini
(eds), Invasione e metastasi, Pacini Editore, Pisa, 1999, pp.
365-379.
- R. Giavazzi & P.-L. Lollini. Saggi in vivo. In: G.
Bevilacqua, R. Giavazzi & P.-L. Lollini (eds), Invasione e
metastasi, Pacini Editore, Pisa, 1999, pp. 387-391.
- K. Scotlandi, M.C. Manara, M. Serra, S. Benini, D. Maurici,
A. Caputo, C. De Giovanni, P.-L. Lollini, P. Nanni, P. Picci, M.
Campanacci, N. Baldini. The expression of P-glycoprotein is
causally related to a less aggressive phenotype in human
osteosarcoma cells. Oncogene, 18, 739-746, 1999. [Medline]
- P. Nanni, G. Forni & P.-L. Lollini. Cytokine gene
therapy: Hopes and pitfalls. Ann. Oncol., 10: 261-266, 1999. [Medline]
- S. Benini, N. Baldini, M.C. Manara, T. Chano, M. Serra, S.
Rizzi, P.-L. Lollini, P. Picci, K. Scotlandi. Redundancy of
autocrine loops in human osteosarcoma. Int. J. Cancer, 80:
581-588, 1999. [Medline]
- F. Cavallo, P. Nanni, P. Dellabona, P.-L. Lollini, G.
Casorati & G. Forni. Strategies for enhancing tumor
immunogenicity. In: T. Blankenstein (ed.) Gene Therapy,
Principles and Applications. Birkhauser Verlag.
1998
- K. Boggio, G. Nicoletti, E. Di Carlo, F. Cavallo, L.
Landuzzi, C. Melani, M. Giovarelli, I. Rossi, P. Nanni, C. De
Giovanni, P. Bouchard, S. Wolf, A. Modesti, P. Musiani, P.-L.
Lollini, M.P. Colombo & G. Forni. Interleukin-12 mediated
prevention of spontaneous mammary adenocarcinomas in Her-2/neu
transgenic mice. J. Exp. Med, 188: 589-596, 1998. [Medline]
- K. Scotlandi, S. Benini, P. Nanni, P.-L. Lollini, G.
Nicoletti, L. Landuzzi, M. Serra, M.C. Manara, P. Picci & N.
Baldini. Blockage of Insulin-like Growth Factor I receptor
inhibits the growth of Ewing's sarcoma in athymic mice. Cancer
Res., 58:4127-4131. [Medline]
- C. De Giovanni, P. Nanni, A. Sacchi, S. Soddu, I. Manni, G.
D'Orazi, S. Bulfone-Paus, T. Pohl, L. Landuzzi, G. Nicoletti, F.
Frabetti, I. Rossi & P.-L. Lollini. Wild-type p53-mediated
down-modulation of IL-15 and IL-15 receptors in human
rhabdomyosarcoma cells. Br. J. Cancer, 78: 1541-1546, 1998. [Medline]
- L. Landuzzi, P. Strippoli, C. De Giovanni, G. Nicoletti, I.
Rossi, R. Tonelli, F. Frabetti, P. Nanni, G.P. Bagnara, P.-L.
Lollini. Production of Stem Cell Factor and expression of c-KIT
in human rhabdomyosarcoma cells: lack of autocrine growth
modulation. Int. J. Cancer, 78: 441-445, 1998. [Medline]
- P.-L. Lollini, G. Nicoletti, L. Landuzzi, C. De Giovanni, I.
Rossi, E. Di Carlo, P. Musiani, W.J. Muller, P. Nanni. Down
regulation of Major Histocompatibility Complex class I expression
in mammary carcinoma of HER-2/neu transgenic mice. Int. J.
Cancer, 77: 937-941, 1998. [Medline]
- P.-L. Lollini, L. Landuzzi, F. Frabetti, I. Rossi, G.
Nicoletti, K. Scotlandi, M. Serra, N. Baldini, C. De Giovanni, P.
Nanni. Expression of functional CD40 on human osteosarcoma and
Ewing's sarcoma cells. Clin. Cancer Res., 4: 1843-1849, 1998. [Medline]
- P. Nanni, I. Rossi, C. De Giovanni, L. Landuzzi, G.
Nicoletti, A. Stoppacciaro, M. Parenza, M.P. Colombo, P.-L.
Lollini. Interleukin 12 gene therapy of MHC-negative murine
melanoma metastases. Cancer Res., 58: 1225-1230, 1998. [Medline]
- P. Nanni, C. De Giovanni, G. Nicoletti, L. Landuzzi, I.
Rossi, F. Frabetti, M. Giovarelli, G. Forni, F. Cavallo, E. Di
Carlo, P. Musiani & P.-L. Lollini. The immune response
elicited by mammary adenocarcinoma cells transduced with
interferon-gamma and cytosine deaminase genes cures lung
metastases by parental cells. Hum. Gene Therapy, 9: 217-224,
1998. [Medline]
- I. Rossi, G. Nicoletti, L. Landuzzi, F. Frabetti, C. De
Giovanni, P. Nanni, P. Musiani, M. Ferrantini, F. Belardelli,
P.-L. Lollini. Inhibition of lung colonisation of a mouse mammary
carcinoma by therapeutic vaccination with interferon-alpha
gene-transduced tumour cells. Clin. Exp. Metastasis, 16: 123-128,
1998. [Medline]
1997 - 1994
- P.-L. Lollini, G. Palmieri, C. De Giovanni, L. Landuzzi, G.
Nicoletti, I. Rossi, C. Griffoni, F. Frabetti, K. Scotlandi, S.
Benini, N. Baldini, A. Santoni, P. Nanni. Expression of
interleukin 15 (IL-15) in human rhabdomyosarcoma, osteosarcoma,
and Ewing's sarcoma. Int. J. Cancer, 71:732-736, 1997.
- E. Di Carlo, A. Modesti, G. Castrilli, L. Landuzzi, A.
Allione, C. De Giovanni, T. Musso, P. Musiani. Interleukin 6 gene
transfected mouse mammary adenocarcinoma: tumor cell growth and
metastatic potential. J. Pathol., 182: 76-85, 1997.
- P. Musiani, A. Modesti, M. Giovarelli, F. Cavallo, M.P.
Colombo, P.-L. Lollini & G. Forni. Cytokines, immunogenicity
and tumour cell death: a question of choice. Immunol. Today, 18:
32-36, 1997.
- P. Nanni, C. De Giovanni, L. Landuzzi, G. Nicoletti, F.
Frabetti, I. Rossi, F. Cavallo, M. Giovarelli, G. Forni &
P.-L. Lollini. Therapy of murine mammary carcinoma metastasis
with interferon gamma and MHC gene-transduced tumour cells. Br.
J. Cancer, 74: 1564-1569, 1996.
- P. Musiani, A. Allione, A. Modica, P.-L. Lollini, M.
Giovarelli, F. Cavallo, F. Belardelli, G. Forni & A. Modesti.
Role of neutrophils and lymphocytes in inhibition of a mouse
mammary adenocarcinoma engineered to release IL-2, IL-4, IL-7,
IL-10, IFN-alpha, IFN-gamma, and TNF-alpha. Lab. Invest., 74:
146-157, 1996.
- K. Scotlandi, M. Serra, M.C. Manara, S. Benini, M. Sarti, D.
Maurici, P.-L. Lollini, P. Picci, F. Bertoni & N. Baldini.
Immunostaining of the p30/32 (MIC2) antigen and molecular
detection of EWS rearrangements for the diagnosis of Ewing's
sarcoma and peripheral neuroectodermal tumor Human Pathol, 27:
480-416, 1996.
- R. Ferracini, M. Olivero, M.F. Di Renzo, M. Martano, C. De
Giovanni, P. Nanni, G. Basso, K. Scotlandi, P.-L. Lollini &
P. Comoglio. Retrogenic expression of the MET proto-oncogene
correlates with the invasive phenotype of human rhabdomyosarcoma.
Oncogene, 12:1697-1706, 1996.
- K. Scotlandi, M. Serra, G. Nicoletti, M. Vaccari, M.C.
Manara, G. Nini, L. Landuzzi, A. Colacci, G. Bacci, F. Bertoni,
P. Picci, M. Campanacci and N. Baldini. Multidrug resistance and
malignancy in human osteosarcoma. Cancer Res., 56: 2434-2439,
1996.
- P.-L. Lollini, P. Nanni, C. De Giovanni, G. Nicoletti &
L. Landuzzi Re: "Randomized trial of adjuvant human interferon
gamma versus observation in high-risk cutaneous melanoma: a
Southwest Oncology Group study" (letter). J. Natl. Cancer Inst.,
88: 926-927, 1996.
- C. De Giovanni, L. Landuzzi, F. Frabetti, G. Nicoletti, C.
Griffoni, I. Rossi, M. Mazzotti, L. Scotto, P. Nanni & P.-L.
Lollini. Antisense Epidermal Growth Factor-Receptor (EGF-R)
transfection impairs proliferative ability of human
rhabdomyosarcoma cells. Cancer Res., 56: 3898-3901, 1996.
- L. Landuzzi, F. Frabetti, I. Rossi, C. Griffoni, C. De
Giovanni, G. Nicoletti, P. Nanni, R. Miniero, G. Palmieri, A.
Santoni & P.-L. Lollini. Expression of transduced
Carcinoembryonic Antigen gene in human rhabdomyosarcoma inhibits
metastasis Cancer Res., 56: 4503-4508, 1996.
- K. Scotlandi, S. Benini, M. Sarti, M. Serra, P.-L. Lollini,
D. Maurici, P. Picci, M.C. Manara & N. Baldini. Insulin-like
Growth Factor I receptor-mediated circuit in Ewing's
sarcoma/peripheral neuroectodermal tumor: a possible therapeutic
target. Cancer Res., 56: 4570-4574, 1996.
- R. Ferracini, M.F. Di Renzo, K. Scotlandi, N. Baldini, M.
Olivero, P.-L. Lollini, O. Cremona, M. Campanacci, P.M. Comoglio.
The Met/HGF receptor is over-expressed in human osteosarcomas and
is activated by either a paracrine or an autocrine circuit.
Oncogene, 10: 739-749, 1995.
- F. Monti, S. Szymczuk, L. Chessa, S. Prudente, G. Nicoletti,
P.P. Fattori, E. Pini, F. Desiderio, E. Pasquini, V. Tison, A.
Ravaioli. Biologic characterization of pleural metastases from
lung adenocarcinoma: description of the new DV90 cell line.
Tumori, 80: 378-384, 1994.
- P.-L. Lollini, A. D'Errico, C. De Giovanni, L. Landuzzi, F.
Frabetti, G. Nicoletti, F. Cavallo, M. Giovarelli, W.F. Grigioni,
P. Nanni. Systemic effects of cytokines released by
gene-transduced tumor cells: marked hyperplasia induced in small
bowel by gamma-interferon transfectants through host's
lymphocytes. Int. J. Cancer, 61: 425-430, 1995.
- P.-L. Lollini, C. De Giovanni, L. Landuzzi, G. Nicoletti, F.
Frabetti, F. Cavallo, M. Giovarelli, G. Forni, A. Modica, A.
Modesti, P. Musiani, P. Nanni. Transduction of genes coding for a
histocompatibility (MHC) antigen and for its physiological
inducer gamma-interferon in the same cell. Efficient MHC
expression and inhibition of tumor and metastasis growth. Human
Gene Ther., 6: 743-752, 1995.
- C. De Giovanni, C. Melani, P. Nanni, L. Landuzzi, G.
Nicoletti, F. Frabetti, C. Griffoni, M.P. Colombo, P.-L. Lollini.
Redundancy of autocrine loops in human rhabdomyosarcoma cells.
Induction of differentiation by suramin. Br. J. Cancer, 72:
1224-1229, 1995.
- F. Dall'Olio, M. Chiricolo, P.-L. Lollini, J.T.Y. Lau. Human
colon cancer cell lines permanently expressing
alpha2,6-sialylated sugar chains by transfection with rat
beta-galactoside alpha2,6-sialyltransferase cDNA. Biochem.
Biophys. Res. Commun., 211: 554-561, 1995.
- M. Giovarelli, P. Musiani, A. Modesti, P. Dellabona, G.
Casorati, A. Allione, M. Consalvo, F. Cavallo, F. di Pierro, C.
De Giovanni, T. Musso & G. Forni. Local release of IL-10 by
transfected mouse mammary adenocarcinoma cells does not suppress
but enhances antitumor reaction and elicits a strong cytotoxic
lymphocyte and antibody-dependent immune memory. J. Immunol.,
155: 3112-3123, 1995.
- P.-L. Lollini & P. Nanni. Minimal requirements for
characterization of cytokine gene-transduced tumor cells: a
proposal. J. Natl Cancer Inst, 87: 1717-1718, 1995.
- P.-L. Lollini, M.C. Bosco, C. De Giovanni, L. Landuzzi, G.
Nicoletti, G. Palmieri, C. Riccardi & P. Nanni. Reduced
oncogenicity and enhanced metastatic spread of IFN-gamma
transfected tumor cells: therapeutic implications. In: G. Forni,
R. Foa', A. Santoni, L. Frati (eds.), Cytokine induced tumor
immunogenicity, Academic Press, 1994, pp. 271-287.
- A. Bontadini, F. Fruet, P.L. Tazzari, P.-L. Lollini, R.
Conte. Comparative analysis of six different white cell-reduction
filters for packed red cells. Transfusion, 34: 531-535,
1994.
- P.-L. Lollini, C. De Giovanni, L. Landuzzi, G. Nicoletti
& P. Nanni. Differentiation of rhabdomyosarcoma cells. In:
J.B. Griffiths, A. Doyle, D.J. Newell (eds.), "Cell and Tissue
Culture: Laboratory Procedures", J. Wiley & Sons, Chichester,
1994, Module 11C:2, pp. 1-14.
- P.-L. Lollini, C. De Giovanni, L. Landuzzi, G. Nicoletti
& P. Nanni. Rhabdomyosarcoma cells in nude mice. In: J.B.
Griffiths, A. Doyle, D.J. Newell (eds.), "Cell and Tissue
Culture: Laboratory Procedure", J. Wiley & Sons, Chichester,
1994, Module 11C:3, pp. 1-9.
- P. Musiani, A. Modesti, M. Brunetti, A. Modica, A. Gulino,
M.C. Bosco, M. Colombo, P. Nanni, F. Cavallo, F. Pericle, M.
Giovarelli, R. Cavallo & G. Forni. The nature and potential
of the reactive response to mouse mammary adenocarcinoma cells
engineered with IL-2, IL-4 or IFN-gamma gene. Natural Immunity,
13: 93-101, 1994.
- K. Scotlandi, M. Serra, M.C. Manara, P.-L. Lollini, D.
Maurici, D. Del Bufalo & N. Baldini. Pretreatment of human
osteosarcoma cells with N-methylformamide enhances P-glycoprotein
expression and resistance to doxorubicin. Int. J. Cancer, 58:
95-101, 1994.
- C. De Giovanni, G. Nicoletti, M. Sensi, A. Santoni, G.
Palmieri, L. Landuzzi, P. Nanni & P.-L. Lollini. H-2Kb and
H-2Db gene transfections in B16 melanoma differently affect
non-immunological properties relevant to the metastatic process.
Involvement of integrin molecules. Int. J. Cancer, 59: 269-274,
1994.
- M. Ferrantini, M. Giovarelli, A. Modesti, P. Musiani, A.
Modica, M. Venditti, E. Peretti, P.-L. Lollini, P. Nanni, G.
Forni & F. Belardelli. IFN-alpha1 gene expression into a
metastatic murine adenocarcinoma (TS/A) results in CD8+ T
cell-mediated tumor rejection and development of antitumor
immunity. Comparative studies with IFN-gamma-producing TS/A
cells. J. Immunol., 153: 4604-4615, 1994.
- A. Allione, M. Consalvo, P. Nanni, P.-L. Lollini, F. Cavallo,
M. Giovarelli, M. Forni, A. Gulino, M.P. Colombo, P. Dellabona,
H. Hock, T. Blankenstein, F.M. Rosenthal, B. Gansbacher, M.C.
Bosco, T. Musso, L. Gusella & G. Forni. Immunizing and
curative potential on replicating and nonreplicating murine
mammary adenocarcinoma cells engineered with IL-2, IL-4, IL-6,
IL-7, IL-10, TNF-alpha, GM-CSF and IFN-gamma gene or admixed with
conventional adjuvants. Cancer Res., 54: 6022-6026, 1994.
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